Anti-biofilm, nitric oxide inhibition and wound healing potential of purpurin-18 phytyl ester isolated from Clinacanthus nutans leaves
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چکیده
منابع مشابه
Antioxidant and Wound Healing Activity of Polyherbal Fractions of Clinacanthus nutans and Elephantopus scaber
Elephantopus scaber and Clinacanthus nutans are traditionally used as wound healing herb. The objective of the present study is to develop a new polyherbal formulation, by comparison, the herbal combination of Elephantopus scaber and Clinacanthus nutans as an in vitro antioxidant activity with their individual herbal activity followed by fractionation of polyherbal formulation for in vivo wound...
متن کاملCerebrosides and a monoacylmonogalactosylglycerol from Clinacanthus nutans.
A mixture of nine cerebrosides and a monoacylmonogalactosylglycerol were separated from the leaves of Clinacanthus nutans. The structures of the cerebrosides were characterized as 1-O-beta-D-glucosides of phytosphingosines, which comprised a common long-chain base, (2S,3S,4R,8Z)-2-amino-8(Z)-octadecene-1,3,4-triol with nine 2-hydroxy fatty acids of varying chain lengths (C(16), C(18), C(20-26))...
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The ethyl acetate fraction from ethanolic extract of Wedelia trilobata (L.) leaves displayed wound healing properties. The ethyl acetate fraction was further subjected to bioassay-guided fractionation which afforded isolation of grandiflorenic acid which requires further investigation to prove its wound healing potential. The grandiflorenic acid from leaves of Wedelia trilobata was assessed for...
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diabetes is characterized by a nitric oxide deficiency at the wound site. diabetes is a factor that influences all stages of wound healing. in animals with acute experimental diabetes induced by streptozotocin (stz), the early inflammatory responses after wounding is impaired, fibroblast and endothelial cell proliferation is reduced as well as accumulation of reparative collagen and gain in wou...
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In the present investigation, methanolic extract of Mimusops elengi leaves were evaluated for wound healing activity. Entire wound healing process is complex series of events that begins at the moment of injury and can continue for months to years. Methanolic extract of Mimusops elengi leaves were examined for wound healing activity in the form of ointment by the excision, the incision and ...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2019.108724